Cellulose TLC Plates

Precise Analysis and Partition Chromatographic Separations of Polar Substances

Cellulose TLC plates work well for demanding high-performance separations. Compared to paper chromatography (PC) TLC, cellulose offers shorter migration times and more concentrated substance spots resulting in higher detection sensitivity.

  • Cellulose 300 plates use native, fibrous cellulose
  • Cellulose 400 plates use high-purity, rod-shaped, microcrystalline cellulose
  • Results in a highly reduced diffusion of analytes
  • Available with/without fluorescent indicators

We also provide special PEI cellulose TLC plates (polyethylenimine-modified cellulose):

  • Act as strong basic anion exchangers
  • Best choice for analyzing substances with exchange-active ionic groups, such as amino acids, peptides, nucleotides, and nucleosides

Typical cellulose tlc plates application include the analysis of amino acids, carbohydrates, phosphates, nucleic acids, and nucleic acid derivatives for:

  • Detection of significantly high increase of amino acids in clinical laboratories
  • Two-dimensional separations such as amino acid “fingerprints”
  • Metabolic studies
Plate Type Description
Cellulose 300 PEI TLC Impregnated cellulose ion exchange layers. Fibrous cellulose impregnated with polyethyleneimine. Recommended application: analysis of nucleic acids, and of mutagenic substances with the 32P-postlabelling procedure.
Cellulose 300 Prep TLC Native fibrous cellulose layers for TLC. Recommended application: partition chromatography of polar substances such as amino acids, carboxylic acids or carbohydrates.
Cellulose 300 TLC Native fibrous cellulose layers for TLC. Recommended application: partition chromatography of polar substances such as amino acids, carboxylic acids or carbohydrates.
Cellulose 400 TLC Microcrystalline cellulose layers for TLC. Prepared by hydrolysis of high purity cellulose with HCl. Recommended application: carboxylic acids, lower alcohols, urea and purine derivatives.