Dry Column Chromatography (DCC)

This technique is useful when you need a fast, easy, and efficient method to purify preparative quantities of substances.

  • Reduced solvent requirements
  • Highly reduced time of solvent removal of purified substances
  • Direct transfer from TLC to column chromatography
  • Load significantly higher quantities than prep TLC: multi-gram scale
  • Comes with UV-254 indicator – visualize separation progress
  • No pumps required; solvent flow is by gravity
  • Both silica and alumina adsorbents are available
  • Nylon foil tubing is solvent resistant and available in 1 – 6 in. diameters
dry column chromatography DCC