NUCLEODUR^® – Sphinx RP

• Distinct selectivity based on bifunctional surface coverage-USP L1 and USP L11
• Pore size 110 Å; particle sizes 1.8 µm, 3 µm, and 5 µm; 14 % C
• A high density of covalently bonded silanes for tailing-free peaks
• Widens the scope for method development
• pH stability 1-10
• Suitable for LC/MS due to low bleeding characteristics
• High reproducibility and consistent quality due to tight QC procedures
• Range of applications: quinolone antibiotics, sulfonamides, xanthines, substituted aromatics

NUCLEODUR Sphinx RP is characterized by exceptional selectivity features generated by a well-balanced ratio of covalently bonded octadecyl and phenyl groups.

The combination of classical hydrophobic with p-p interactions (aromatic ring system) expands the scope of selectivity in comparison with conventional reversed-phase packings.

NUCLEODUR Sphinx RP is suited for separating molecules containing aromatic and multiple bonds. It’s recommended for the separation of polar compounds, outperforms many customary C18 phases.

In addition, exhaustive endcapping steps minimize unwanted surface silanol activity and guarantee excellent peak shapes even for strong basic analytes.

Different from standard phenyl phases, NUCLEODUR Sphinx RP is far more stable towards hydrolysis and is also suggested for LC/MS applications.

Due to the additional intermolecular interactions, NUCLEODUR Sphinx RP is an interesting replenishment to the high density bonded phases NUCLEODUR C8/C18 Gravity and the polar endcapped NUCLEODUR C18 Pyramid