Chromatography Flash Cartridges, Flash Columns

Achieve Increased Speed, Tighter Elution Bands, and Greater Loading Capacity with Sorbtech Flash Columns

Flash chromatography cartridges, also called flash columns, help you accelerate research while getting more value from your budget. With Sorbtech Purity™ Pre-Packed and EZ Flash Columns (empty) options, you gain flexibility for different workflows. In addition, each cartridge is manufactured from solvent-resistant polypropylene. Therefore, the columns can withstand harsh purification conditions and deliver reliable performance every time.

Flash Chromatography Cartridges - Sorbtech Purity

Advantages of pre-packed vs. self-packed

  • Achieve faster purifications by running at higher pressures
  • Load larger samples with the use of finer particle silica
  • Get reproducible results from run to run through consistent packing
  • Improve safety by eliminating the risk of glass column breakage
Purity Flash Cartridge

Purity™ Pre-Packed

Features of Sorbtech Purity™ Flash Cartridges

  • Boost speed, resolution, and loading capacity with proprietary packing methods
  • Rely on leak-free cartridges that handle pressures up to 400 psi
  • Gain better results from cartridges packed with Premium Rf Silica Gel
  • Prevent solvent channeling using a uniform, homogeneous bed
  • Choose the right fit from a wide range of sizes, 4 g to 3 kg, all using the same adsorbent
EZ Empty Flash Cartridges

EZ Empty Flash Cartridge

Features of Sorbtech EZ Flash Columns

  • Enjoy easy usability with a convenient screw-top design
  • Customize performance by packing the column with adsorbents of your choice
  • Save on costs with replaceable frits that allow simple flash column repacking
  • Rely on durability as solvent-resistant polypropylene withstands pressures up to 200 psi

Full Compatibility With Most Flash Systems

  • Sorbtech™ EZ Flash System
  • SepaBean™ Machine
  • Teledyne Isco™
  • Biotage™
  • Agilent Technologies™
  • Interchim™
  • Grace Discovery Sciences™
  • Buchi™ systems

What Are Flash Columns and Why Are They Used?

Flash columns, also known as flash chromatography cartridges, are a core tool for purification in organic and analytical chemistry. They hold an adsorbent, typically silica gel or alumina, that serves as the stationary phase. When a mixture passes through the column under pressure, compounds separate based on polarity and affinity. Therefore, flash columns give chemists a fast, efficient, and cost-effective way to isolate desired products from complex mixtures.

The Purpose of Flash Columns in the Lab

The main purpose of flash columns is to speed up purification. Unlike traditional gravity columns, flash columns use pressure or automated systems to push solvents through quickly. As a result, they shorten purification times, increase throughput, and improve reproducibility. In addition, modern pre-packed flash columns ensure consistent packing density, which provides reliable separations from run to run and reduces user error.

Common Use Cases for Flash Chromatography

Chromatographers often rely on flash columns in a variety of workflows. For example, they are widely used in pharmaceutical labs to purify drug candidates and intermediates. They also serve in natural products chemistry, where researchers isolate alkaloids, terpenes, and other plant compounds. In addition, academic teaching labs use flash columns to demonstrate the principles of separation science. Furthermore, industrial R&D teams often choose flash columns for scale-up experiments, where they need reproducible and cost-effective purification before committing to larger HPLC methods.

Most importantly, flash columns balance speed, efficiency, and reliability—making them a practical choice for any lab that needs quick, high-quality separations.