Spherical Silica Gel – HPLC Semi-Prep Grade

HPLC Semi-Prep Grade is well-suited for the packing of analytical, semi-preparative, and preparative HPLC columns.

The abundant silanol groups on the surface are readily accessible for hydrophilic interactions with more polar compounds which generally are retained longer, making them ideally suited for the purification of chemical synthesis intermediates, oils, fats, and natural products (vitamins, flavors, fragrances, etc.)

HPLC Semi-Prep Grade is available in porosities of 70Å, 100Å, 300Å, and 500Å and particle sizes of 5µm, 10µm, and 15µm.

Quality and diversity

HPLC Semi-Prep Grade utilizes Sorbtech’s Premium Rf™ Spherical Silica Gel which boasts narrow pore and particle distributions, ensuring optimal selectivity, capacity, efficiency, low operating pressure, and shorter processing time.

Purity

Premium Rf™ Spherical Silica Gel is manufactured to a high chemical purity standard (99.95% SiO2). Organics and trace metals content are controlled within stringent limits. Each production batch has undergone extensive quality control testing to ensure reliable lot-to-lot performance. This rigid control of chemical purity, surface area, and pore size, ensure our silica will yield reproducible separation results and allow for direct scale-up without requiring time-consuming method redevelopment.

Robust

Our spherical silicas are mechanically robust and can, therefore, be repacked multiple times in either analytical or preparative scale columns.

Spherical Silica Gel - Premium Rf Advantages
Features Benefits
Narrow particle size distribution
  • Higher (Sharper) resolution
  • More reliable resolution
Minimal fines
 This means the backpressure is lower and faster run time.
Uniform porosity
 High loading – which means you can load up to 30% more than granular – which means you can do fewer runs.
Minimal small pores
 Lower risk of trapped solute in pores – which means you don’t lose your expensive sample.
Small pore volume
  • High bulk density – which means more silica in the same column – which leads to higher loading.
  • Lower “dead” volume – which means less solvent use.
Low metal content
 Low interference of analytes (High Purity - 99.95% SiO2) and (individual metal content < 100 ppm) – which means you won’t have peak tailing with certain types of molecules.
Mechanically stable spheres
  • Stable rigid bed – which means the column bed won’t collapse, and you won’t have to replace the column so often.
  • Significantly less fine particle generation – which means the backpressure won’t gradually increase until the column is unusable.
Catalog No.DescriptionPrice (USD)
74200-001Spherical Silica Gel, Premium Rf, 150A, 5um, 10g Inquire
74300-001Spherical Silica Gel, Premium Rf, 150A, 10um, 10g Inquire

Premium Rf™
Individual Metals Content is <100 ppm.

Item *Typical Specifications
Na 45 ppm
Mg 1 ppm
Al 2 ppm
Ca 2 ppm
Fe 5 ppm
Zr 15 ppm
Ti 40 ppm
*Not lot specific
Catalog No. Particle Dist. Porosity pH Value Loss on Drying Bulk Density Surface Area Pore Volume Compound Size
72200 5 µm 70 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml 450-550 m2/g 0.80 ml/g <1,000 Daltons
73200 5 µm 100 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml 250-350 m2/g 0.80 ml/g <10,000 Daltons
74200 5 µm 150 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~170 m2/g 0.80 ml/g <10,000 Daltons
75200 5 µm 200 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~140 m2/g 0.80 ml/g <10,000 Daltons
76200 5 µm 300 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~90 m2/g 0.80 ml/g <10,000 Daltons
77200 5 µm 500 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~55 m2/g 0.80 ml/g <50,000 Daltons
72300 10 µm 70 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml 450-550 m2/g 0.80 ml/g <1,000 Daltons
73300 10 µm 100 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml 250-350 m2/g 0.80 ml/g <10,000 Daltons
74300 10 µm 150 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~170 m2/g 0.80 ml/g <10,000 Daltons
75300 10 µm 200 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~140 m2/g 0.80 ml/g <10,000 Daltons
76300 10 µm 300 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~90 m2/g 0.80 ml/g <10,000 Daltons
77300 10 µm 500 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~55 m2/g 0.80 ml/g <50,000 Daltons
72400 15 µm 70 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml 450-550 m2/g 0.80 ml/g <1,000 Daltons
73400 15 µm 100 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml 250-350 m2/g 0.80 ml/g <10,000 Daltons
74400 15 µm 150 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~170 m2/g 0.80 ml/g <10,000 Daltons
75400 15 µm 200 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~140 m2/g 0.80 ml/g <10,000 Daltons
76400 15 µm 300 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~90 m2/g 0.80 ml/g <10,000 Daltons
77400 15 µm 500 Å 4.0 – 7.0 ≤ 2.0% 0.45 g/ml ~55 m2/g 0.80 ml/g <50,000 Daltons