Sepabeads & Diaion Resins
Diaion HP20 synthetic adsorbent resin is a macroporous styrenic polymeric bead type resin designed for adsorption/desorption process scale applications. Its matrix provides an aromatic non-polar surface with excellent selectivity for hydrophobic areas of molecules, including biomolecules like antibiotics via low energy van der Waal’s interactions. It is remarkable for its wide pore polymeric structure which provides excellent broad spectrum adsorption characteristics. Diaion HP21 has slightly smaller pores, and slightly higher surface area than Diaion HP20.
Diaion HP2MG is a macroporous methacrylate polymeric resin. It has no aromatic character. Diaion HP2MG grades have different selectivity than the classic Diaion HP20. It is recommended for broad spectrum adsorption and desorption of small and large molecules, long chain aliphatic molecules, decolorization and desalting applications, and should be evaluated as an alternate resin matrix to the styrenic based adsorbents.
| Product | Matrix Type | Ceph C Capacity* (g/L) | Water Retention (%) | Shipping Density (g/L) | Particle Size Distribution | Brandname |
|---|---|---|---|---|---|---|
| HP20 | Highly Porous (styrene, DVB) | ~38 | 55-65 | ~680 | On 250 µm: 90% min | Diaion |
| HP21 | Highly Porous (styrene, DVB) | ~40 | 45-55 | ~685 | On 250 µm: 90% min | Diaion |
| HP2MG | (Methacrylate) | <10 | 55-65 | ~720 | On 250 µm: 90% min | Diaion |
| Product | Effective Size (mm) | Surface Area (m²/dry-g) | Pore Volume (mL/g) | Pore Radius (Å) | Specific Gravity | Swelling Water to Toluene | Operation Temperatures |
|---|---|---|---|---|---|---|---|
| HP20 | 0.25 min | ~590 | ~1.3 | 290 | 1.01 | 30% | 130°C max. |
| HP21 | 0.25 min | ~640 | ~1.3 | 110 | 1.01 | 30% | 130°C max. |
| HP2MG | 0.30 min | ~570 | ~1.3 | 240 | 1.09 | 5% | - |
The Sepabeads SP825, SP850, and SP700 resins provide a smaller more uniform pore size distribution and higher surface area as compared to Diaion HP20. The increase in surface area is approximately 2x traditional adsorbents, and nearly matches the surface area of activated carbon. In many applications, this means twice the working capacity for the same volume of resin. They are recommended for industrial chemical process applications, bio/pharmaceutical applications such as desalting and extraction, and waste treatment.
Sepabeads SP70 and SP710 are premium grade resins designed for the debittering of juices and related food products. These high surface area resins offer excellent kinetics and high capacity for naringin (and other bittering agents). They meet the compositional requirements for Secondary Direct Food Additives (21 CFR Section 173.65). Sepabeads SP70 and S710 are also provided pre-conditioned to meet the extractive requirements on the date of manufacture.
The Sepabeads SP207 resin is a macroporous chemically modified brominated styrenic polymeric type resin. The bromination of the aromatic ring provides increased hydrophobicity, and consequently, increased selectivity for hydrophobic molecules versus conventional styrene/DVB synthetic adsorbents like Diaion HP20 resin. In addition, the bromination increases the resin density which allows for settling in fermentation broths, and for usage in upflow fluidized beds.
| Product | Matrix Type | Ceph C Capacity* (g/L) | Water Retention (%) | Shipping Density (g/L) | Particle Size Distribution | Brandname |
|---|---|---|---|---|---|---|
| SP825L | Highly Porous (styrene, DVB) | ~80 | 52-62 | ~685 | On 250 µm: 90% min | Sepabeads |
| SP850 | Highly Porous (styrene, DVB) | ~85 | 46-52 | ~695 | On 250 µm: 90% min | Sepabeads |
| SP700 | Highly Porous (styrene, DVB) | ~85 | 60-70 | ~680 | On 250 µm: 90% min | Sepabeads |
| SP70 | Highly Porous (styrene, DVB) | - | 55-65 | ~685 | On 250 µm: 90% min | Sepabeads |
| SP710 | Highly Porous (styrene, DVB) | - | 60-70 | ~685 | On 250 µm: 90% min | Sepabeads |
| SP207 | (Brominated styrene-DVB) | ~120 | 43-53 | ~790 | On 250 µm: 90% min | Sepabeads |
| Product | Effective Size (mm) | Surface Area (m2/dry-g) | Pore Volume (mL/g) | Pore Radius (Å) | Specific Gravity | Swelling Water to Toluene | Operation Temperatures |
|---|---|---|---|---|---|---|---|
| SP825L | 0.25 min | ~930 | ~1.4 | 70 | 1.01 | 20% | 130°C max. |
| SP850 | 0.25 min | ~930 | ~1.1 | 45 | 1.01 | 20% | 130°C max. |
| SP700 | 0.25 min | ~1200 | ~2.3 | 90 | 1.01 | 7% | 130°C max. |
| SP70 | 0.25 min | ~870 | ~1.5 | 70 | 1.01 | 24% | 130°C max. |
| SP710 | 0.25 min | ~900 | - | 90 | 1.01 | - | 130°C max. |
| SP207 | 0.25 min | ~600 | ~1.0 | 110 | 1.19 | 20% | 130°C max. |