Published On: January 27th, 2023Categories: HPLCComments Off on Syringe Filters, An Introduction

Syringe filters are small, cylindrical devices that are used to filter liquids or gases before they are injected into a syringe. They are commonly used in laboratory settings to remove impurities from samples or to sterilize a liquid before it is injected into a patient. There are a variety of different types available, each with their own unique characteristics and applications.

The most common types are made from cellulose acetate, polypropylene, or nylon. Cellulose acetate filters are commonly used for aqueous solutions and are known for their high flow rate and low protein binding. Polypropylene filters, on the other hand, are more resistant to chemicals and can withstand higher temperatures. Nylon filters are often used for organic solvents and are known for their high chemical resistance.

Syringe filters are used in a wide range of applications, including biotechnology, pharmaceuticals, and clinical research. In the biotechnology field, they are used to purify proteins and other biomolecules. In the pharmaceutical industry, they are used to filter and sterilize injectable drugs. In clinical research, they are used to filter and sterilize samples before they are analyzed. Overall, syringe filters play a crucial role in many different fields and are an important tool in the laboratory setting.

CHROMAFIL Syringe Filters Feature:

  • Different membrane types to meet multiple filtration applications
  • Low extractable, sonic welded, leak-free polypropylene housings
  • Fast flow geometry for minimized back pressure during filtration
  • Very low hold-up volumes for maximum volume recovery
  • Certified clean for HPLC and UPLC analysis
  • Standard Luer-Lok™ inlet and Luer slip outlet
  • Designed to be compatible for use on all common automated filtration systems,
    e.g. SOTAX® dissolution systems

Features:

  • Polypropylene Housing
    Better solvent stability compared to acrylate and polystyrene filters
  • Shells ultrasonically sealed, not glued
    No extractable components from glues
  • Filtration in both directions possible
    The liquid cannot bypass the membranes.
  • Luer-lok on side of entry
    Safe connection on the “high pressure” side
  • Luer exit
    Standard luer for 3 mm and 25 mm filters, minispike luer with low dead volume and small OD for 15 mm filters
  • Deflector
    The stream of liquid is broken and distributed, and does not directly hit the membrane: this prevents rupture of the membrane
  • Star-shaped distribution device
    The liquid is evenly distributed to the whole membrane surface: This results in a better utilization of the total area. The filter is not plugged up rapidly, providing high flow efficiency.
  • Color Coded
    Filter with 0.2 µm pores have a yellow upper shell and filters with 0.45 µm pores are colorless. The different membrane types are distinguished by different colors.
  • Low Dead Volume
    ~120 µl for 25 mm Ø, 12 µl for 15 mm Ø, 5 µl for 3 mm Ø
syringe filters product family